The Disney production beat out Ben Stiller and the Farrelly brothers' "The Heartbreak Kid," which pulled in $14 million.
The Rock plays the superstar quarterback of the fictitious Boston Rebels football team, who discovers he has an 8-year-old daughter from a brief marriage in his youth.
Dwayne The Rock Johnson, Kyra Sedgwick, Roselyn Sanchez, and Madison Pettis pose with Tubbs, Spike the bulldog in the movie, at the premiere of The Game Plan. Photo from Yahoo News.